I am a
Home I AM A Search Login

Papers of the Week

Papers: 4 May 2019 - 10 May 2019

2019 May 07

Curr Diab Rep



Painful and Painless Diabetic Neuropathies: What Is the Difference?


Shillo P, Sloan G, Greig M, Hunt L, Selvarajah D, Elliott J, Gandhi R, Wilkinson ID, Tesfaye S
Curr Diab Rep. 2019 May 07; 19(6):32.
PMID: 31065863.


The prevalence of diabetes mellitus and its chronic complications are increasing to epidemic proportions. This will unfortunately result in massive increases in diabetic distal symmetrical polyneuropathy (DPN) and its troublesome sequelae, including disabling neuropathic pain (painful-DPN), which affects around 25% of patients with diabetes. Why these patients develop neuropathic pain, while others with a similar degree of neuropathy do not, is not clearly understood. This review will look at recent advances that may shed some light on the differences between painful and painless-DPN.