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Papers of the Week

Papers: 4 May 2019 - 10 May 2019

Human Studies, Pharmacology/Drug Development

2019 Oct 01

Pain Med



The Impact of Surgical Amputation and Valproic Acid on Pain and Functional Trajectory: Results from the Veterans Integrated Pain Evaluation Research (VIPER) Randomized, Double-Blinded Placebo-Controlled Trial.


Buchheit T, John Hsia H-L, Cooter M, Shortell C, Kent M, McDuffie M, Shaw A, Buckenmaier C T, Van de Ven T
Pain Med. 2019 Oct 01; 20(10):2004-2017.
PMID: 31045229.


To determine if the perioperative administration of valproic acid reduces the incidence of chronic pain three months after amputation or revision surgery.