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Papers of the Week

Papers: 27 Apr 2019 - 3 May 2019

2019 Jul

Brain Behav Immun


Neuroimmune interactions in chronic pain – an interdisciplinary perspective.


Hore Z, Denk F
Brain Behav Immun. 2019 Jul; 79:56-62.
PMID: 31029795.


It is widely accepted that communication between the nervous and immune systems is involved in the development of chronic pain. At each level of the nervous system, immune cells have been reported to accompany and frequently mediate dysfunction of nociceptive circuitry; however the exact mechanisms are not fully understood. One way to speed up progress in this area is to increase interdisciplinary cross-talk. This review sets out to summarize what pain research has already learnt, or indeed might still learn, from examining peripheral and central nociceptive mechanisms using tools and perspectives from other fields like immunology, inflammation biology or the study of stress.