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Papers of the Week

2019 Apr 17

J Headache Pain



Relationship between changes in resting-state spontaneous brain activity and cognitive impairment in patients with CADASIL.


Su J, Wang M, Ban S, Wang L, Cheng X, Hua F, Tang Y, Zhou H, Zhai Y, Du X, Liu J
J Headache Pain. 2019 Apr 17; 20(1):36.
PMID: 30995925.


Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) mainly manifests with cognitive impairment. Cognitive deficits in patients with CADASIL are correlated with structural brain changes such as lacunar lesion burden, normalized brain volume, and anterior thalamic radiation lesions, but changes in resting-state functional brain activity in patients with CADASIL have not been reported.