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Papers of the Week

2019 Apr 11

Health Qual Life Outcomes



A systematic literature review of patient-reported outcome measures used in gout: an evaluation of their content and measurement properties.


Janssen CA, Oude Voshaar MAH, Ten Klooster PM, Jansen T TLA, Vonkeman HE, van de Laar MAFJ
Health Qual Life Outcomes. 2019 Apr 11; 17(1):63.
PMID: 30975212.


Gout is a common, monosodium urate crystal-driven inflammatory arthritis. Besides its clinical manifestations, patients often also suffer from pain, physical impairment, emotional distress and work productivity loss, as a result of the disease. Patient-reported outcome measures (PROMs) are commonly used to assess these consequences of the disease. However, current instrument endorsements for measuring such outcomes in acute and chronic gout clinical settings are based on limited psychometric evidence. The objective of this systematic literature review was to identify currently available PROMs for gout, and to critically evaluate their content and psychometric properties, in order to evaluate the current status regarding PROMs for use in gout patients.