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Papers of the Week

Papers: 6 Apr 2019 - 12 Apr 2019

Human Studies, Pharmacology/Drug Development

2019 May

Reg Anesth Pain Med



Prognostic value of hypersensitivity reactions on epidural steroid injection outcomes: a phenotypic signature? A prospective cohort study.


Cohen S, Doshi T, Dawson T, Gupta A, Durbhakula S, Constantinescu OC, Jacobs M, Verdun AV, Salisu M, Griffith SR, Kurihara C
Reg Anesth Pain Med. 2019 May; 44(5):586-594.
PMID: 30962251.


Studies have found that diffuse pain, indicative of central sensitization, portends poor interventional outcomes. Multiple chemical sensitivities are associated with signs of central sensitization. We sought to prospectively determine whether hypersensitivity reactions (HR) were associated with epidural steroid injection (ESI) outcomes.