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Papers of the Week

Papers: 6 Apr 2019 - 12 Apr 2019

Human Studies, Pharmacology/Drug Development

2019 Apr 01

J Natl Compr Canc Netw



Efficacy of Oral Cryotherapy During Oxaliplatin Infusion in Preventing Oral Thermal Hyperalgesia: A Randomized Trial.


Bauman B, Mick R, Martinez E, Lawless TM, Zinck L, Sinclair P, Fuhrer M, O'Hara M, Schneider CJ, O'Dwyer P, Plastaras J, Teitelbaum U, Reiss KA
J Natl Compr Canc Netw. 2019 Apr 01; 17(4):358-364.
PMID: 30959472.


Chemotherapy-induced oral thermal hyperalgesia (OTH) is a common and debilitating side effect of platinum-based anticancer agents. This study evaluated the efficacy of oral cryotherapy in preventing OTH during oxaliplatin chemotherapy infusion.