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Papers of the Week

2019 Oct




Effect of Long-Term Intrathecal Bupivacaine Infusion on Blood Pressure.


Hayek SM, McEwan MT, Veizi E, Roh J, Ali O, Katta S, Hunter J, Delozier SJ, Deer TR
Neuromodulation. 2019 Oct; 22(7):811-817.
PMID: 30951233.


The local anesthetic bupivacaine is a common analgesic adjuvant medication used in combination with opioids in intrathecal drug delivery systems (IDDSs). While the acute effects of spinal bupivacaine injection on blood pressure (BP) have been studied, there is a dearth of data regarding long-term effects of continuous intrathecal bupivacaine infusion.