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Papers of the Week

Papers: 30 Mar 2019 - 5 Apr 2019

Human Studies

2019 Nov 01

Pain Med



An Exploratory Study of Endogenous Pain Modulatory Function in Patients Following Mild Traumatic Brain Injury.


Carey C, Saxe J, White FA, Naugle KM
Pain Med. 2019 Nov 01; 20(11):2198-2207.
PMID: 30938813.


Recent animal research suggests that mild traumatic brain injury (mTBI) facilitates abnormal endogenous modulation of pain, potentially underlying the increased risk for persistent headaches following injury. However, no human studies have directly assessed the functioning of endogenous facilitory and inhibitory systems in the early stages after an mTBI.