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Papers of the Week

2019 Jun

Reg Anesth Pain Med



Fentanyl versus remifentanil-based TIVA for pediatric scoliosis repair: does it matter?


Kars MS, Villacres Mori B, Ahn S, Merwin S, Wendolowski S, Gecelter R, Rothman A, Poon S
Reg Anesth Pain Med. 2019 Jun; 44(6):627-631.
PMID: 30923248.


Opioid-induced hyperalgesia (OIH) and acute opioid tolerance have been demonstrated extensively in patients undergoing adolescent idiopathic scoliosis (AIS) repair. Remifentanil infusion has been strongly linked to both tolerance and OIH in these patients; however, the impact of using an intraoperative fentanyl infusion has not been well studied. This study aims to determine if patients undergoing operative management of AIS have decreased opioid consumption and pain scores when an intraoperative fentanyl infusion is used as compared with a remifentanil infusion.