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Papers of the Week

Papers: 23 Mar 2019 - 29 Mar 2019

Pharmacology/Drug Development

2019 Apr

Neurosurg Clin N Am



Intrathecal Pain Therapy for the Management of Chronic Noncancer Pain.


Sukul VV
Neurosurg Clin N Am. 2019 Apr; 30(2):195-201.
PMID: 30898270.


Intrathecal drug delivery has been well established an effective and safe method for the treatment of pain, including palliative cancer-related and chronic nonmalignant pain. In this article, we discuss the role of intrathecal pain therapy in the management of chronic, refractory nonmalignant pain. Common indications, patient selection criteria, medication options, complications, and adverse events are discussed within the context of results from randomized controlled trials, clinical consensus guidelines, and best available literature to date.