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Papers of the Week

Papers: 16 Mar 2019 - 22 Mar 2019

2019 May

Curr Opin Hematol



Pain and sickle cell disease.


Aich A, Jones MK, Gupta K
Curr Opin Hematol. 2019 May; 26(3):131-138.
PMID: 30893088.


Pain is a major comorbidity of sickle cell disease (SCD). Opioids are the mainstay for pain treatment but remain suboptimal. We discuss mechanism-based treatable targets devoid of opioids to prevent and/or treat SCD pain.