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Papers of the Week

Papers: 16 Mar 2019 - 22 Mar 2019

Human Studies, Pharmacology/Drug Development

2019 Sep

Arthritis Rheumatol



Randomized, Double-Blind, Placebo-Controlled Trial of Intra-articular CNTX-4975 (trans-capsaicin) for Pain Associated With Osteoarthritis of the Knee.


Stevens RM, Ervin J, Nezzer J, Nieves Y, Guedes K, Burges R, Hanson PD, Campbell JN
Arthritis Rheumatol. 2019 Sep; 71(9):1524-1533.
PMID: 30888737.


The TRIUMPH study assessed the efficacy and safety of high-purity synthetic trans-capsaicin (CNTX-4975) in subjects with chronic osteoarthritis-associated moderate to severe knee pain.