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Papers of the Week

2019 May

J Fish Biol



Behavioural and physiological effects of methadone in the perioperative period on the Nile tilapia Oreochromis niloticus.


Crivelaro RM, Thiesen R, Aldrovani M, Silva PES, Barros Sobrinho AAF, Moraes PC
J Fish Biol. 2019 May; 94(5):823-827.
PMID: 30868600.


Through the analysis of behavioural changes, this study demonstrates that methadone has behavioural, but not analgesic, effects on Oreochromis niloticus. It provides information that suggests the drug has sedative abilities, as the recovery time was shorter in the fish receiving methadone. Future research, with different doses and stimuli, is required to provide more information about analgesia.