Pelvic inflammatory disease (PID) is a frequent cause of acute abdomen among sexually active females, although rarely seen in girls prior to their sexual debut. In this case report, a 12-year-old girl was hospitalised due to abdominal pain. She was virgo and premenarcheal. A laparoscopy showed a normal appendix but revealed pyosalpinx. A follow-up with ultrasound of the genitalia interna showed normal relations. PID should be considered in all females with compatible symptoms, irrespective of their age.