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Papers of the Week

2019 Mar

Somatosens Mot Res



Characterization of traumatic spinal cord injury model in relation to neuropathic pain in the rat.


Batista C M, Mariano E D, Onuchic F, Dale C S, Dos Santos G B, Cristante A F, Otoch J P, Teixeira M J, Morgalla M, Lepski G
Somatosens Mot Res. 2019 Mar; 36(1):14-23.
PMID: 30870070.


Purpose/aim: Neuropathic pain following spinal cord injury (SCI) has a tremendous impact on patient's quality of life, and frequently is the most limiting aspect of the disease. In view of the severity of this condition and the absence of effective treatments, the establishment of a reliable animal model that reproduces neuropathic pain after injury is crucial for a better understanding of the pathophysiology and for the development of new therapeutic strategies. Thus, the objective of the present study was to standardize the traumatic SCI model in relation to neuropathic pain.