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Papers of the Week

2019 Jun

Curr Opin Endocrinol Diabetes Obes



Opioid induced adrenal insufficiency: what is new?


Donegan D
Curr Opin Endocrinol Diabetes Obes. 2019 Jun; 26(3):133-138.
PMID: 30870182.


Despite the declaration of an opioid epidemic, opioid use remains prevalent. Side-effects of chronic opioid use continue to be problematic. Opioid-induced endocrinopathies have been well documented, yet opioid-induced adrenal insufficiency (OIAI) remains underappreciated. This review summarizes what is currently known regarding the prevalence, predictive factors for the development and effect of treatment of OIAI.