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Papers of the Week

Papers: 16 Mar 2019 - 22 Mar 2019

Human Studies

2019 May 15

J Neurosci Methods


Long term reliability of nociceptive withdrawal reflex thresholds.


Herm C, Silbereisen V, Graf BM, Lassen CL
J Neurosci Methods. 2019 May 15; 320:44-49.
PMID: 30871985.


The nociceptive withdrawal reflex (NWR) is a polysynaptic spinal reflex protecting the body from harmful stimuli. Two different methods to assess its' threshold (NWR-T) have been part of clinical trials concerning the evaluation of the nociceptive system in the human body. NWR-T's are gathered by stimulation at the sole of the foot and over the sural pathway. Consequently, EMG analyzes the muscle activity over the biceps femoris and tibialis anterior muscle. Past studies favor stimulation at the sole of the foot.