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Papers of the Week

Papers: 2 Mar 2019 - 8 Mar 2019

2019 Mar 04

Curr Rheumatol Rep



Descending Control Mechanisms and Chronic Pain.


Chen QL, Heinricher MM
Curr Rheumatol Rep. 2019 Mar 04; 21(5):13.
PMID: 30830471.


The goal of the review was to highlight recent advances in our understanding of descending pain-modulating systems and how these contribute to persistent pain states, with an emphasis on the current state of knowledge around "bottom-up" (sensory) and "top-down" (higher structures mediating cognitive and emotional processing) influences on pain-modulating circuits.