I am a
Home I AM A Search Login

Papers of the Week

Papers: 23 Feb 2019 - 1 Mar 2019

Animal Studies


J Pain Res


Characterization of novel lnc RNAs in the spinal cord of rats with lumbar disc herniation.


Wang Q, Ai H, Liu J, Xu M, Zhou Z, Qian C, Xie Y, Yan J
J Pain Res. 2019; 12:501-512.
PMID: 30787629.


Radicular pain, caused by a lesion or autologous nucleus pulposus (NP) implantation, is associated with alteration in gene expression of the pain-signaling pathways. lncRNAs have been shown to play critical roles in neuropathic pain. However, the mechanistic function of lncRNAs in lumbar disc herniation (LDH) remains largely unknown. Identifying different lncRNA expression under sham and NP-implantation conditions in the spinal cord is important for understanding the molecular mechanisms of radicular pain.