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Papers of the Week

Papers: 9 Feb 2019 - 15 Feb 2019

Animal Studies

2019 Nov

Int J Dev Neurosci


Repeated neonatal needle-prick stimulation increases inflammatory mechanical hypersensitivity in adult rats.


de Carvalho R C, Prado L, Rissardo Oliveira N C, Vilela Giusti F C, Santos Vieira J, Giusti-Paiva A, da Silva J R T, da Silva M L
Int J Dev Neurosci. 2019 Nov; 78:191-197.
PMID: 30742972.


Newborn infants are vulnerable to procedural stress and pain exposure on the first weeks of life that represents a critical period for the development of nociceptive, sensory, emotional, and social functions. We evaluated the nociceptive behavior of adult male and female rats that were submitted to nociceptive experience in the neonatal period and the maternal behavior in the postnatal period.