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Papers of the Week

Papers: 19 Jan 2019 - 25 Jan 2019

Animal Studies, Pharmacology/Drug Development


J Pain Res


Analgesic effects of calcitonin on radicular pain in male rats.


Terashima Y, Takebayashi T, Jimbo S, Ogon I, Sato T, Ichise N, Tohse N, Yamashita T
J Pain Res. 2019; 12:223-230.
PMID: 30655691.


Radicular pain is a frequently observed symptom of lumbar disk herniation or lumbar spinal canal stenosis. Achieving radicular pain relief is difficult. This type of pain may progress to chronic neuropathic pain. Calcitonin (elcatonin [eCT]) has been used mainly for hypercalcemia and pain associated with osteoporosis. The purpose of this study was to investigate analgesic effects of repeated eCT administration on radicular pain in male rats and changes in mRNA-expression levels of voltage-dependent sodium channels in the dorsal root ganglion (DRG).