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Papers of the Week

Papers: 12 Jan 2019 - 18 Jan 2019

Animal Studies

2019 Jul

Arthritis Rheumatol



Non-invasive mechanical joint loading as an alternative model for osteoarthritic pain.


Ter Heegde F, Luiz AP, Santana-Varela S, Chessell IP, Welsh F, Wood JN, Chenu C
Arthritis Rheumatol. 2019 Jul; 71(7):1078-1088.
PMID: 30638309.


Mechanisms responsible for osteoarthritic pain remain poorly understood and current analgesic therapies are often insufficient. We have characterized and pharmacologically tested the pain phenotype of a non-invasive mechanical joint loading (MJL) model of osteoarthritis thus providing an alternative murine model for osteoarthritic pain.