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Papers of the Week

Papers: 12 Jan 2019 - 18 Jan 2019

Human Studies

2019 Mar

J Am Coll Surg



Preemptive Treatment of Phantom and Residual Limb Pain with Targeted Muscle Reinnervation at the Time of Major Limb Amputation.


Valerio IL, Dumanian GA, Jordan SW, Mioton LM, Bowen BJ, West JM, Porter K, Ko JH, Souza JM, Potter BK
J Am Coll Surg. 2019 Mar; 228(3):217-226.
PMID: 30634038.


A majority of the nearly two million Americans living with limb loss suffer from chronic pain in the form of neuroma-related residual limb and phantom limb pain (PLP). Targeted muscle reinnervation (TMR) surgically transfers amputated nerves to nearby motor nerves for prevention of neuroma. The objective of this study was to determine whether TMR at the time of major limb amputation decreases the incidence and severity of PLP and residual limb pain.