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Papers of the Week

2018 Jul

ARYA Atheroscler



The effect of tadalafil on functional capacity and echocardiographic parameters in patients with repaired Tetralogy of Fallot.


Sabri M R, Shoja M, Shoja M, Hosseinzadeh M
ARYA Atheroscler. 2018 Jul; 14(4):177-182.
PMID: 30627194.


Tetralogy of Fallot (TOF) is one of the most common cyanotic congenital heart diseases (CHD) in children. Various surgical procedures including palliative shunts and TOF total correction (TFTC) were done with some complications, of which, the most common is pulmonary valve regurgitation (PR). Tadalafil is a phosphodiesterase 5 inhibitor which reduces pulmonary vascular resistance, and improves right ventricular function and vascular endothelium, and may have some beneficial effects after TFTC.