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Papers of the Week


2019 Jan 09


Rev Med Suisse


15


N° 632-633

[Neurology].

Authors

Eskioglou E, Benninger D, Di Virgilio G, Hirt L, Kuntzer T, Michel P, Novy J, Rossetti AO, Rouaud O, Ryvlin P, Theaudin M, Du Pasquier R
Rev Med Suisse. 2019 Jan 09; 15(N° 632-633):74-77.
PMID: 30629375.

Abstract

Thrombolysis and late thrombectomy can be performed in case of compatible radiological imaging. Anti-CGRP monoclonal antibodies seem more effective for the treatment of migraine. Siponimod can reduce significantly disability progression in secondarily progressive MS. Brand-to-generic levetiracetam switching does not cause recrudescence of epileptic seizures. A new definition of Alzheimer's disease using biomarkers of cerebrospinal fluid (CSF) and imaging provides a better understanding of the underlying mechanisms. The use of levodopa-carbidopa intestinal gel and a subcutaneous apomorphine infusion allow a reduction of motor fluctuations in Parkinson's disease. Eculizumab appears as an alternative treatment in severe forms of myasthenia gravis.