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Papers of the Week

Papers: 5 Jan 2019 - 11 Jan 2019

Animal Studies

2019 Apr

Osteoarthritis Cartilage



Characterisation of peripheral and central components of the rat monoiodoacetate model of Osteoarthritis.


Lockwood SM, Lopes DM, McMahon SB, Dickenson AH
Osteoarthritis Cartilage. 2019 Apr; 27(4):712-722.
PMID: 30611904.


Pain is the main reason patients report Osteoarthritis (OA), yet current analgesics remain relatively ineffective. This study investigated both peripheral and central mechanisms that lead to the development of OA associated chronic pain.