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Papers of the Week

Papers: 5 Jan 2019 - 11 Jan 2019

Human Studies, Pharmacology/Drug Development

2019 Aug

Support Care Cancer



High concentration of topical amitriptyline for treating chemotherapy-induced neuropathies.


Rossignol J, Cozzi B, Liebaert F, Hatton S, Viallard M-L, Hermine O, Greco C
Support Care Cancer. 2019 Aug; 27(8):3053-3059.
PMID: 30607681.


Chemotherapy-induced peripheral neuropathy (CIPN) is a devastating pain condition of cancer therapy that may force chemotherapy dose reduction or discontinuation. Since treatment options for CIPN are quite limited, we investigated the effect of 10% amitriptyline cream on neuropathic pain.