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The modulation effects of repeated transcutaneous auricular vagus nerve stimulation on the functional connectivity of key brainstem regions along the vagus nerve pathway in migraine patients.

Previous studies have shown a significant response to acute transcutaneous vagus nerve stimulation (taVNS) in regions of the vagus nerve pathway, including the nucleus tractus solitarius (NTS), raphe nucleus (RN) […]

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Objective wearable measures and subjective questionnaires for predicting response to neurostimulation in people with chronic pain.

Neurostimulation is an effective therapy for treating and management of refractory chronic pain. However, the complex nature of pain and infrequent in-clinic visits, determining subject’s long-term response to the therapy […]

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The effects of high-definition transcranial direct current stimulation on pain modulation and stress-induced hyperalgesia.

The dorsolateral prefrontal cortex (DLPFC) has been implicated in the modulation of pain-related signals. Given this involvement, manipulation of the DLPFC through transcranial direct current stimulation (tDCS) may influence internal […]

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Intrathecal Drug Delivery Systems for Cancer Pain Control: Insights on Current Contemporary Practices in the US.

Among patients with cancer with moderate to severe, intractable pain, intrathecal drug delivery using an intrathecal drug delivery system (IDDS) offers effective pain control. In this study, we evaluate the […]

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Transcranial direct current stimulation alleviates nociceptive behavior in male rats with neuropathic pain by regulating oxidative stress and reducing neuroinflammation.

Transcranial direct curent stimulation (tDCS) and trans-spinal direct current stimulation (tsDCS) are promising therapies for pain that can alter the excitability of neuronal activity in cerebral cortex. The aim of […]

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Six-Month Follow-up of a Trial of Spinal Cord Burst Stimulation vs Placebo Stimulation and Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery.

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Research hotspots and trends on spinal cord stimulation for pain treatment: a two-decade bibliometric analysis.

Chronic pain poses a significant social burden. Spinal cord stimulation (SCS) is considered to be the most promising treatment for refractory pain. The aim of this study was to summarize […]

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Altered functional brain network patterns in patients with migraine without aura after transcutaneous auricular vagus nerve stimulation.

Transcutaneous auricular vagus nerve stimulation (taVNS) shows excellent effects on relieving clinical symptoms in migraine patients. Nevertheless, the neurological mechanisms of taVNS for migraineurs remain unclear. In recent years, voxel-wise […]

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Can pain under anesthesia be measured? Pain-related brain function using functional near-infrared spectroscopy during knee surgery.

Quantitative measurement of perisurgical brain function may provide insights into the processes contributing to acute and chronic postsurgical pain.

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Transcranial Direct Current Stimulation Attenuates Chronic Pain in Knee Osteoarthritis by Modulating BDNF/TrkB Signaling in the Descending Pain Modulation System.

Knee osteoarthritis (KOA) is the most common cause of chronic pain, but its pain mechanisms are complex and may be closely related to the descending pain modulation system. Transcranial direct […]

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