Rejected

The use of nonsteroidal anti-inflammatory drugs is an effective adjunct in managing perioperative pain. We sought to determine if the use of intraoperative ketorolac as part of a multimodal ERAS protocol increased the risk of bleeding complications in breast surgery.

This meta-analysis of randomized controlled trials (RCTs) examined the efficacy and safety of minocycline for three major mental disorders: schizophrenia, bipolar disorder and major depressive disorder (MDD).

Male Chronic Pelvic Pain Syndrome (MCPPS) is a complex condition and difficult to decipher due to the multifactorial etiologies and system interrelationships. No studies to date have described a movement-based, multisystem assessment including the musculoskeletal, visceral, nervous, lymphatic and vascular systems, as well as manual prostate mobility testing. The purpose of this paper is to demonstrate the importance of a comprehensive physical therapy evaluation to identify predominant mechanical and movement-based dysfunctions related to multiple anatomical structures and their interrelationships. Furthermore, symptoms and potentially confounding psychosocial, and environmental factors linked to MCPPS will be presented, and an overview of prospective treatment will be provided.

Lumbar spine injuries (LSIs) are common in both men's and women's National Collegiate Athletic Association (NCAA) basketball players and can frequently lead to reinjuries and persistent pain.

Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2-to end preventable child deaths by 2030-we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000-2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations.

This cross sectional study was carried out on incomplete abortion cases in Obstetrics and Gynaecology (ObG) Department, Sir Salimullah Medical College and Mitford Hospital (SSMC & MH), Dhaka, Bangladesh. It was carried out from 1st January 2012 to 30th June 2012 to assess the effectiveness of MVA in terms of completeness, duration, cost and complication of the procedure and duration of hospital stay. Incomplete abortion cases attending the ObG indoor were considered as study population. A total of 50 patients were collected by purposive sampling. Inclusion criteria were: i) Incomplete abortion up to 12 weeks of gestation, ii) Failed medical abortion and iii) Incomplete MR. Exclusion criteria were: i) Induced abortion, ii) Septic abortion with fever, iii) Haemodynamically unstable patients. Counseling was done to provide emotional support during the procedure. Pain management was done by paracervical block, analgesia and or mild sedation. During MVA, measures taken to prevent infection. Complication like excessive pervaginal bleeding and incomplete evacuation was assessed by ultrasonogram. Duration of hospital stay and total cost were assessed. Limitation of the study: short sample, short follow-up, small population not enough for a reproducible data. Further study needed in future. Mean age of the patients was 21-30 years. Most of them were grand multipara (36%), 70% belong to below average income group, 44% of them never used contraceptives. Many of the incomplete abortion cases presented with 9-10 weeks (66%) of gestation with per vaginal bleeding (96%). Lower abdominal pain (66%), passage of fleshy mass (14%). 88% of them are mildly anaemic and 12% were severely anaemic. Eighty two percent (82%) of them were haemodynamically stable and 18% were haemodynamiclly unstable. The mean time of the procedure was 6-10 minutes. Most of the patients (82%) did not need any resuscitation after the procedure. For 25% cases, analgesics had to be used. Four percent (4%) cases had complication like incomplete evacuation and excessive p/v bleeding after the procedure.

The Ceylon krait () is a highly venomous elapid snake endemic to Sri Lanka. Its bites are rare and only seven reports are found in the literature. Therefore, the clinical manifestations and natural history of envenoming of Ceylon krait are not well studied yet. Neuroparalysis is the main clinical manifestation of their bites. We report two cases of proven Ceylon krait bites of two young snake keepers working in a serpentarium. They developed acute neuroparalysis, abdominal pain and a period of amnesia. The first patient developed myalgia and increased level of serum creatine kinase suggestive of rhabdomyolysis. One was treated with Indian polyvalent antivenom and both recovered with some long-lasting clinical disabilities namely impairment of sensation of the bitten arm and persistent refraction errors in the eyes in the first patient. The second patient had persistent marked nystagmus.

Dexmedetomidine (Dex) has been used adjuvant in Transversus abdominis plane (TAP) blocks. This meta-analysis was aimed at evaluating the effect of Dex in TAP blocks.

Perineuritis is a rare type of peripheral neuropathy defined by swelling and cellular infiltration in the perineurium. We herein report a 52-year-old man who presented with subacute onset pain from the back to the lower limbs, muscle weakness and hypoesthesia. A sural nerve biopsy revealed perineuritis, consisting of inflammatory cell infiltration and swelling of the perineurium. Oral prednisolone, plasma exchange and intravenous immunoglobulin treatment were all effective, leading to significant improvement of the symptoms.