Rejected

Identifying personal characteristics associated with sustaining a concussion is of great interest, yet only a few have examined this in children. The purpose of this study was to examine the association between sex, neurodevelopmental disorders, health history, and lifetime history of self-reported concussion in 12- and 13-year-old athletes.

Readmissions after PCI are a burden to patients and health services that are not well understood.

Small studies have suggested an association between vertigo and psychiatric comorbidity. The purpose of this study is to evaluate the associations between vertigo and cognitive and psychiatric conditions among a large sample of U.S. children.

Ibuprofen (IBU), a common non-steroidal anti-inflammatory drug (NSAID), is widely used by humans for controlling fever and pain, and is frequently detected in the influent of wastewater treatment plants and different aquatic environments. In this study, the biotransformation of IBU in activated sludge (AS), anaerobic methanogenic sludge (AnMS) and sulfate-reducing bacteria (SRB)-enriched sludge systems was investigated at three different concentrations of 100, 500 and 1000 μg/L via a series of batch and continuous studies. IBU at concentration of 100 μg/L was effectively biodegraded by AS whereas AnMS and SRB-enriched sludge were less effective in IBU biodegradation at all concentrations tested. However, at higher IBU concentrations of 500 and 1000 μg/L, AS showed poor IBU biodegradation and chemical oxygen demand (COD) removal due to inhibition of aerobic heterotrophic bacteria (i.e., Candidatus Competibacter) by IBU and/or IBU biotransformation products. The microbial analyses showed that IBU addition shifted the microbial community structure in AS, AnMS and SRB-enriched sludge systems, however, the removals of COD, nitrogen and sulfur in both anaerobic sludge systems were not affected significantly (p > 0.05). The findings of this study provided a new insight into biotransformation of IBU in three important biological sludge systems.

8-week glecaprevir/pibrentasvir demonstrates high rates of sustained virological response at post-treatment week 12 (SVR12) across hepatitis C virus (HCV) genotypes (GT) 1-6 in treatment-naïve patients without cirrhosis. We evaluated glecaprevir/pibrentasvir once daily for 8 weeks in treatment-naïve patients with compensated cirrhosis.

Individuals with cancer commonly experience functional impairments. Symptoms may present immediately or years to decades following their treatment. These impairments may include fatigue, pain, neuropathy, lymphedema, or radiation fibrosis syndrome and have the potential to deleteriously impact their function and quality of life. Cancer rehabilitation is a comprehensive resource that facilitates maximizing and maintaining cancer survivors' physical, social, psychological, and vocational functioning. This article covers the common functional impairments experienced by cancer survivors and the treatment strategies used in cancer rehabilitation. Application of these services can enhance the ongoing care for cancer survivors.

Several studies suggest that systemic magnesium reduces postoperative opioid consumption and the intensity of pain, but others report conflicting results. The efficacy and safety profile of intravenous magnesium in noncardiac surgery remain uncertain.

Suicidal thoughts are common among veterans with posttraumatic stress disorder (PTSD). The aim of this study was to examine the prevalence and correlates of four courses of suicidal (SI) among veterans receiving residential PTSD treatment.