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Profile of Lasmiditan in the Acute Treatment of Migraine in Adults: Design, Development, and Place in Therapy.

Migraine is a common neurological disorder that is present in a large proportion of the global population. It is estimated to occur in around 20.7% of women and 10.7% of […]

Acupuncture and related therapies for tension-type headache: a systematic review and network meta-analysis.

Tension-type headache (TTH) is one of the most common primary headaches. Several studies have confirmed the efficacy of acupuncture therapies for TTH, but it is uncertain which treatment is most […]

Pain management in dermatology.

The dermatologist has to deal with many situations where the patient feels pain, and must therefore know how to manage it.

The Role of MicroRNA in Migraine: A Systemic Literature Review.

Migraine is a common primary headache disorder, affecting about 14% of the population. Importantly, it was indicated as the second cause of disability globally and the leading cause among young […]

The 5-HT receptor as the target of ditans in migraine – from bench to bedside.

Migraine is a leading cause of disability in more than one billion people worldwide, yet it remains universally underappreciated, even by individuals with the condition. Among other shortcomings, current treatments […]

Cutaneous Electroanalgesia for Relief of Chronic and Neuropathic Pain.

Role of autophagy in the pathogenesis and regulation of pain.

Pain is a ubiquitous and highly concerned clinical symptom, usually caused by peripheral or central nervous injury, tissue damage, or other diseases. The long-term existence of pain can seriously affect […]

Pharmaceutical aspects of novel CGRP inhibitors used in the prophylaxis and treatment of migraine.

Migraine is one of the most prevalent neurological disorders known to have an immense adverse socio-economic impact. Neurogenic inflammation is thought to mediate migraine, and CGRP is known to be […]

Central generators of migraine and autonomic cephalalgias as targets for personalized pain management: Translational links.

Migraine oscillates between different states in association with internal homeostatic functions and biological rhythms that become more easily dysregulated in genetically susceptible individuals. Clinical and pre-clinical data on migraine pathophysiology […]

Role of proprioceptors in chronic musculoskeletal pain.

What is the topic of this review? Why proprioceptors, which are non-nociceptive, low-threshold mechanosensory neurons that monitor muscle contraction and body position, express several proton-sensing ion channels and receptors. What […]

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