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Pain-Related Anxiety in Spanish-Speaking Mexican Americans who Report Chronic Pain: Psychometric Evaluation of a New Spanish Adaptation of the 20-Item Pain Anxiety Symptom Scale (PASS-20).

The 20-item Pain Anxiety Symptom Scale (PASS-20) was adapted for Spanish-speaking Mexican Americans who report chronic pain (SSMACP). The instrument measures pain-related anxiety with fear, physiological, avoidance/escape, and cognitive anxiety […]

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Classical and Non-Classical Psychedelic Drugs Induce Common Network Changes in Human Cortex.

The neurobiology of the psychedelic experience is not fully understood. Identifying common brain network changes induced by both classical (i.e., acting at the 5-HT receptor) and non-classical psychedelics would provide […]

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Treatment with delgocitinib cream improves itch, pain and other signs and symptoms of chronic hand eczema: Results from the Hand Eczema Symptom Diary in a phase IIb randomized clinical trial.

Measuring patient-reported outcomes is crucial to fully capture the burden of chronic hand eczema (CHE).

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Intrathecal non-viral interleukin-10 gene therapy ameliorates neuropathic pain as measured by both classical static allodynia and a novel supra-spinally mediated painassay, theTwo-ArmRodentSomatosensory (TARS)task.

Intrathecal delivery of interleukin-10 (IL-10) gene therapy has been reported to be effective in suppressing pain enhancement in a variety of rodent models. However, all publications that have tested this […]

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Treating Chronic Pain in Sickle Cell Disease – The Need for a Biopsychosocial Model.

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The Utility of a Novel, Combined Biofeedback-Virtual Reality Device as Add-on Treatment for Chronic Migraine: A Randomized Pilot Study.

To determine if frequent use of a combined biofeedback-virtual reality device improves headache-related outcomes in chronic migraine.

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“You have to believe the patient”: What do people with fibromyalgia find helpful (and hindering) when accessing health care?

Fibromyalgia (FM) is a complex, still poorly understood, and difficult-to-treat chronic pain condition for which many people struggle to find adequate care.

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Migraine and the Gender Divide.

Migraine is a global neurologic disease that is highly prevalent, especially in women. Studies have observed a predisposition for the development of migraine in women, although the mechanisms involved have […]

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Get your head in the game: a replicated single-case-experimental-design evaluating the effect of a novel virtual reality intervention in people with chronic low back pain.

Chronic low back pain (CLBP) is a leading cause of disability worldwide. Contemporary treatment of CLBP is suboptimal, with small/moderate effect sizes and high relapse rates. Virtual reality (VR) is […]

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The benefits of making peace with pain: Chronic pain acceptance moderates the indirect effect of perceived burdensomeness between pain severity and suicidal cognitions.

The purpose of this study was 1) to examine the degree to which perceived burdensomeness mediates the relationship between pain severity and suicidal cognitions, and 2) to determine whether this […]

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