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Long-Term Opioid Use and Dementia Risk in Patients With Chronic Pain.

This study aimed to investigate the association between long-term opioid use and the risk of dementia in patients with chronic pain.

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Qualitative Analysis of Patient Perspectives of Buprenorphine After Transitioning from Long-Term, Full-Agonist Opioid Therapy Among Veterans with Chronic Pain.

Guidelines recommend consideration of modification, tapering, or discontinuation of long-term, full-agonist opioid therapy when harms outweigh benefits; one alternative to tapering or discontinuing full-agonist opioids for the management of chronic […]

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Body mindsets are associated with pain and threat-related risk factors for pain in survivors of childhood cancer.

Pain is a common consequence of childhood cancer. While most research has examined biomedical predictors of post-cancer pain, biopsychosocial conceptualisations such as the Cancer Threat Interpretation (CTI) model hold promise […]

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Biopsychosocial Factors Associated with Pain and Pain-Related Outcomes in Adults and Children with Sickle Cell Disease: A Multivariable Analysis of the GRNDaD Multi-Center Registry.

Pain is the primary symptomatic manifestation of sickle cell disease (SCD), an inherited hemoglobinopathy. The characteristics that influence pain experiences and outcomes in SCD are not fully understood. The primary […]

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Extracellular RNAs-TLR3 signaling contributes to cognitive impairment after chronic neuropathic pain in mice.

Chronic pain is often associated with cognitive decline, which could influence the quality of the patient’s life. Recent studies have suggested that Toll-like receptor 3 (TLR3) is crucial for memory […]

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The Potential of Psychedelics for the Treatment of Episodic Migraine.

This review presents the existing literature of and a framework for how psychedelic drugs might be applied as therapeutic agents in episodic migraine.

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Chronic Pain and Mood Disorders Are Not Barriers to Symptom Improvement Under Collaborative Co-managed Care (C).

Patients with comorbid chronic pain and mood disorders have more severe gastrointestinal disease and higher healthcare expenses than their peers. We sought to determine whether management under our innovative Collaborative […]

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Evaluation of a therapist-guided virtual psychological pain management program when provided as routine care: A prospective pragmatic cohort study.

Numerous randomised controlled trials have evaluated the outcomes of internet-delivered psychological pain management programs (PMPs) as a way of increasing access to care for people with chronic pain. However, there […]

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Participant-Generated Timelines: A Participatory Tool to Explore Young People With Chronic Pain and Parents’ Narratives of Their Healthcare Experiences.

Visual methods are becoming more evident in health research. Timeline drawings have been used as a participatory tool alongside interviews in life course research. In this article, we describe how […]

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Psychological treatments for the management of pain after musculoskeletal injury: a systematic review and meta-analysis.

Musculoskeletal injury is a leading cause of pain and disability worldwide; 35% to 75% of people experience persistent pain for months and years after injury. Psychological treatments can reduce pain, […]

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