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Unique Considerations in Episodic Migraine: Underserved Populations.

Episodic migraine is a common and disabling neurological disorder that is underdiagnosed and undertreated. Additional barriers are put in place for those who belong to an underserved population. This could […]

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‘I Will Fight for People to Not Have the Experience I’ve Had’: A Thematic Analysis of the Experiences and Perspectives of Chronic Pain Lived Experience Advocates.

Navigating the healthcare system with chronic pain, alongside navigating the experience of the chronic pain itself, is recognised to be highly challenging. Frequently available interventions do not fully meet the […]

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Coexistence of neuropathic corneal pain, corneal nerve abnormalities, depression, and low quality of life.

To evaluate the quality of life (QoL), mental health conditions and corneal morphology in neuropathic corneal pain (NCP) subjects without a significant ocular surface disease.

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Improved sleep affects epigastric pain in functional dyspepsia by reducing the levels of inflammatory mediators.

The pathogenesis of epigastric pain in functional dyspepsia (FD) is complex. The study aims to explore the effect of sleep improvement on this symptom.

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Sound-induced analgesia cannot always be observed in adult mice.

Music seems promising as an adjuvant pain treatment in humans, while its mechanism remains to be illustrated. In rodent models of chronic pain, few studies reported the analgesic effect of […]

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Psychopathology Associated with Chronic Pruritus: A Systematic Review.

There are no previous studies of the psychopathology associated with different aetiologies of chronic pruritus. A systematic review was performed of cohort and case-control studies comparing healthy controls with patients […]

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Impact of headache frequency and preventive medication failure on quality of life, functioning, and costs among individuals with migraine across several European countries: need for effective preventive treatment.

Data are limited regarding the combined impact of headache frequency and failure of preventive medication (efficacy and/or tolerability) on the humanistic/economic burden of migraine.

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Virtual reality to understand pain-associated approach behaviour: a proof-of-concept study.

Pain-associated approach and avoidance behaviours are critically involved in the development and maintenance of chronic pain. Empirical research suggests a key role of operant learning mechanisms, and first experimental paradigms […]

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A glutamatergic DRN-VTA pathway modulates neuropathic pain and comorbid anhedonia-like behavior in mice.

Chronic pain causes both physical suffering and comorbid mental symptoms such as anhedonia. However, the neural circuits and molecular mechanisms underlying these maladaptive behaviors remain elusive. Here using a mouse […]

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JAAD Game Changers: Use of oral antidepressants in patients with chronic pruritus: A systematic review.

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