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Migraines and cardiovascular disease: mechanisms and methodological challenges.

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Functional genomic mechanisms of opioid action and opioid use disorder: a systematic review of animal models and human studies.

In the past two decades, over-prescription of opioids for pain management has driven a steep increase in opioid use disorder (OUD) and death by overdose, exerting a dramatic toll on […]

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Inhibition of C5aR1 as a promising approach to treat taxane-induced neuropathy.

Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of several antitumor agents resulting in progressive and often irreversible damage of peripheral nerves. In addition to their known anticancer effects, […]

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Identification of opioid use disorder using electronic health records: Beyond diagnostic codes.

We used structured and unstructured electronic health record (EHR) data to develop and validate an approach to identify moderate/severe opioid use disorder (OUD) that includes individuals without prescription opioid use […]

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Identification of the Minimal Disease Activity Domains Achieved Based on Different Treatments in Psoriatic Arthritis.

The aim of this work is to characterize which Minimal Disease Activity (MDA) domains are mainly achieved, based on different treatments, in psoriatic arthritis (PsA) patients. Moreover, the association between […]

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Identifying patients with opioid use disorder using International Classification of Diseases (ICD) codes: Challenges and opportunities.

International Classification of Diseases (ICD) diagnosis codes are often used in research to identify patients with opioid use disorder (OUD), but their accuracy for this purpose is not fully evaluated. […]

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The association between multiple sclerosis and migraine: A meta-analysis.

Multiple sclerosis (MS) is a chronic progressive condition marked by the deterioration of myelin and impairment of neurological function. The global prevalence of MS is approximately 2.2 million. Migraines are […]

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Adolescent alcohol exposure produces sex-specific long-term hyperalgesia via changes in central amygdala circuit function.

Exposure to alcohol during adolescence produces many effects that last well into adulthood. Acute alcohol is analgesic and people living with pain report drinking alcohol to reduce pain, but chronic […]

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Migraine in older adults.

Migraine is an evolving, and sometimes lifelong disorder. The prevalence of episodic migraine peaks among individuals aged in their late 30s, implying a tendency for the disorder to remit with […]

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The Influence of Pain on Reduced Quality of Life in Patients with Hidradenitis Suppurativa: A Single-Center Retrospective Study.

Pain and itch are impactful and burdensome symptoms of hidradenitis suppurativa (HS). Elucidating factors associated with pain and itch severity may identify groups disproportionally affected by HS-related pain and itch […]

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