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Depression treatment initiation among patients with versus without chronic pain.

The purpose of this study was to examine the extent to which the presence of chronic non-cancer pain (CNCP) impacts the likelihood that patients with diagnoses of depression will initiate […]

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Elevated prelimbic cortex-to-basolateral amygdala circuit activity mediates comorbid anxiety-like behaviors in chronic pain.

Chronic pain could cause both hyperalgesia and anxiety symptoms. How the two components are encoded in the brain remains unclear. The prelimbic cortex (PrL), a critical brain region for both […]

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The putative role of neuroinflammation in the complex pathophysiology of migraine: From bench to bedside.

The implications of neurogenic inflammation and neuroinflammation in the pathophysiology of migraine have been clearly demonstrated in preclinical migraine models involving several sites relevant in the trigemino-vascular system, including dural […]

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Overview of radiotherapy-induced chronic pain in childhood cancer survivors: A narrative review.

Radiotherapy is an important aspect of oncological treatment in several childhood cancers. However, radiotherapy is known to have numerous side effects, including detrimental effects on growth, neurocognitive impairment, and the […]

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Demoralization and Suicidal Ideation in Chronic Pain Patients.

The literature has clearly stressed that patients suffering from chronic pain are at high risk of suicidal behavior (SB). Hence the need to improve the characterization of this behavior risk […]

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Interrelationships of Sleep Quality, Obesity Severity, and Clinical Headache Features among Women with Comorbid Migraine and Obesity.

Obesity and migraine are often comorbid. Poor sleep quality is also common among individuals with migraine and may be influenced by comorbidities such as obesity. However, understanding of migraine’s relationship […]

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“INTEGRO INTEGRated Psychotherapeutic InterventiOn” on the Management of Chronic Pain in Patients with Fibromyalgia: The Role of the Therapeutic Relationship.

Fibromyalgia (FM) is a chronic disease characterized by a heterogeneous set of physical and psychological conditions. The chronic experience of disability felt by patients and the impact on quality of […]

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Clinical Utility of a mHealth Assisted Intervention for Activity Modulation in Chronic Pain: The Pilot Implementation of Pain ROADMAP.

Being able to successfully self-regulate one’s activity levels is a key adaptation strategy for many people with chronic pain. This study aimed to explore the clinical utility of a mobile […]

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It is one or the other: No overlap between healthy individuals perceiving thermal grill illusion or paradoxical heat sensation.

Paradoxical heat sensation (PHS) and the thermal grill illusion (TGI) are both related to the perception of warmth or heat from innocuous cold stimuli. Despite being described as similar perceptual […]

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Enhancing Exposure Treatment for Youths With Chronic Pain: Co-design and Qualitative Approach.

Increasing the access to and improving the impact of pain treatments is of utmost importance, especially among youths with chronic pain. The engagement of patients as research partners (in contrast […]

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