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New migraine drugs.

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Other primary headaches: Distinct clinical features and uncertain pathophysiology.

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Efficacy, safety and indirect comparisons of lasmiditan, rimegepant, and ubrogepant for the acute treatment of migraine: A systematic review and network meta-analysis of the literature.

We performed a random-effects network meta-analysis to study the efficacy and safety of newly developed drugs for the acute treatment of migraine attacks.

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Cephalalgia – The early history.

The journal was founded in 1980 and was first published in 1981. The foundation was mainly laid by Ottar Sjaastad who also served as the first Editor-in-Chief. In the early […]

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Update on headaches associated with physical exertion.

Headaches associated with physical exertion include headache precipitated by coughing or other Valsalva maneuvers, headache brought on by prolonged physical exercise, sexual headaches and cardiac cephalalgia.

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Whole Exome Sequencing of Hemiplegic Migraine Patients Shows an Increased Burden of Missense Variants in CACNA1H and CACNA1I Genes.

Hemiplegic migraine (HM) is a rare subtype of migraine with aura. Given that causal missense mutations in the voltage-gated calcium channel α1A subunit gene CACNA1A have been identified in a […]

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Safety and tolerability of monoclonal antibodies targeting the CGRP pathway and gepants in migraine prevention: A systematic review and network meta-analysis.

Direct comparisons of the tolerability and safety of migraine preventive treatments targeting the calcitonin gene-related peptide pathway are lacking. This study aimed to compare the safety and tolerability of anti-calcitonin […]

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Sensorimotor gating in chronic migraine and its association to bilateral greater occipital nerve block.

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Update on primary headache associated with sexual activity and primary thunderclap headache.

This narrative review aims to provide an update on primary headache associated with sexual activity and primary thunderclap headache.

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Hypnic Headache – What do we know in 2022?

Hypnic Headache, also known as “alarm clock headache”, is a rare primary headache disorder. It is characterized by frequently recurring headache attacks, which only develop during sleep, especially nighttime sleep.

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