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Methodological considerations on real-world evidence studies of monoclonal antibodies against the CGRP-pathway for migraine: a systematic review.

Real-world data are accumulating on the effectiveness, tolerability and safety of anti-calcitonin gene-related peptide pathway monoclonal antibodies for the preventive treatment of migraine. We performed a systematic review of the […]

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Epigenetic Connections of the TRPA1 Ion Channel in Pain Transmission and Neurogenic Inflammation – a Therapeutic Perspective in Migraine?

Persistent reprogramming of epigenetic pattern leads to changes in gene expression observed in many neurological disorders. Transient receptor potential cation channel subfamily A member 1 (TRPA1), a member of the […]

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Inhibition of persistent sodium current reduces spreading depression-evoked allodynia in a mouse model of migraine with aura.

We investigated the efficacy of inhibiting persistent Na+ currents (INaP) in acute rodent models of migraine with aura. Cortical spreading depression (SD) is a slow wave of neuronal and glial […]

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From diet to disasters, lifestyle factors can affect headaches and migraine.

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Two-year, real-world erenumab persistence and quality of life data in 82 pooled patients with abrupt onset, unremitting, treatment refractory headache and a migraine phenotype: New daily persistent headache or persistent post-traumatic headache in the majority of cases.

Patients diagnosed with New Daily Persistent Headache and Persistent Post-Traumatic Headache belong to a heterogeneous group of primary and secondary headache disorders, with the common clinical feature that these conditions […]

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American Headache Society 65th Annual Scientific Meeting June 15-18, 2023 Austin, Texas.

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Randomized controlled pilot trial of prazosin for prophylaxis of posttraumatic headaches in active-duty service members and veterans.

Evaluate the efficacy and tolerability of prazosin for prophylaxis of headaches following mild traumatic brain injury in active-duty service members and military veterans.

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Headache clinicians’ perspectives on the remote monitoring of patients’ electronic diary data: A qualitative study.

We assessed headache clinicians’ viewpoints on potential remote access to patients’ digital headache diary data and the practicalities of data utilization.

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Long-term efficacy and safety of erenumab in patients with chronic migraine and acute medication overuse: A subgroup analysis.

Assess the long-term efficacy and safety of erenumab in patients with chronic migraine with acute medication overuse.

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Living in society, living with migraine: Editorial for the 2022 Members’ Choice Award paper.

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