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Papers: 5 April 2025 - 11 April 2025

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Human assembloid model of the ascending neural sensory pathway.

Somatosensory pathways convey crucial information about pain, touch, itch and body part movement from peripheral organs to the central nervous system. Despite substantial needs to understand how these pathways assemble […]

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The dorsal column nuclei scale mechanical sensitivity in naive and neuropathic pain states.

During pathological conditions, tactile stimuli can aberrantly engage nociceptive pathways leading to the perception of touch as pain, known as mechanical allodynia. The brain stem dorsal column nuclei integrate tactile […]

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Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution

Microglia, essential in the central nervous system (CNS), were historically considered absent from the peripheral nervous system (PNS). Here, we show a PNS-resident macrophage population that shares transcriptomic and epigenetic […]

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