A neurologist by training, I am the Director of the Interdisciplinary Center for Pain Medicine and Translational Pain Research in the Department of Neurology at University Medicine Essen. My interdisciplinary research group focuses on the interactions between pain and cognition. Our research addresses the CNS mechanisms underlying nociception, pain, and pain modulation in health and disease using scientific methods that range from the cognitive neurosciences to clinical studies. Translation to treatment inspires our work on the role of treatment expectations and prior experiences on analgesic treatment outcomes. As speaker of the collaborative research center “Treatment Expectations“, funded by the German Research Foundation, I am dedicated to fostering national and international collaboration, building support structures for the next generation of scientists, and communicating scientific knowledge to patients and the public.