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Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients.

The identification of predictors of response to antiCGRP mAbs could favor tailored therapies and personalized treatment plans. This study is aimed at investigating predictors of ≥ 50%, ≥ 75% and 100% response at 24 weeks in patients with high-frequency episodic (HFEM: 8-14 days/month) or chronic migraine (CM).

TRPA1 activation in non-sensory supporting cells contributes to regulation of cochlear sensitivity after acoustic trauma.

Heat-Dependent Loop Melting Drives TRPV1 Opening.

A mesocorticolimbic signature of pleasure in the human brain.

Biological Sex Influences the Contribution of Sign-Tracking and Anxiety-Like Behaviour toward Remifentanil Self-Administration.

TRPV1-mediated sonogenetic neuromodulation of motor cortex in freely moving mice.

Multi-omics Analysis Identifies IgG2b Class-Switching with ALCAM-CD6 Co-Stimulation in Lymph Nodes During Advanced Inflammatory-Erosive Arthritis.

The neuroprotective effects of estrogen and estrogenic compounds in spinal cord injury.

Chronic intermittent propofol attenuates surgery-induced neuroinflammation, apoptosis, and cognitive impairment in aged mice.

Sensitisation of colonic nociceptors by IL-13 is dependent on JAK and p38 MAPK activity.

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