Pain Research Forum Highlights

Aug 19, 2020

Pain Research Forum Highlights Collection:


Analgesia From General Anesthetics: A “Pain-Off” Switch in the Central Amygdala

Isoflurane and ketamine engage a pain-suppression circuit controlled by GABAergic neurons in the CeA

Does Dendritic Spine Plasticity Contribute to Pain? The Evidence Is Mushrooming

Two-photon imaging study links changes in the structure of dorsal horn dendritic spines to neuropathic pain, in a mouse spared nerve injury model

When Mice Make Faces, Machine Learning to the Rescue!

Algorithm identifies and classifies characteristic expressions in response to emotional events; calcium imaging reveals neuronal underpinnings

Switch to Telehealth During COVID-19 Pandemic Seen as “Silver Lining” of a Great “Natural Experiment”

Clinics move rapidly to virtual care



Building an Evidence Base in Chiropractic Medicine: A Conversation With Petra Schweinhardt

Dr. Schweinhardt discusses what attracted her to musculoskeletal pain research, how to build an evidence base in chiropractic medicine, and much more.

The Pain Beat (Episode 1) – Pain Targets: Molecules? Cells? Circuits? Systems?

What biological levels should be targeted to produce the most effective pain therapies: molecules, cells, circuits, or systems?

The Pain Beat (Episode 2) – Optogenetics and Chemogenetics for Pain Treatment: How Feasible Are They? How Effective Could They Be?

Are optogenetics and chemogenetics feasible approaches to pain treatment and, if so, how effective might they be?

The 2020 PRF Virtual Correspondents Blog

Eight early-career pain researchers are taking part in PRF’s science communications training program, blogging about hot topics in pain research



Psychological Treatments for Chronic Low Back Pain: A Focus on Mechanisms

Melissa Day, PhD, University of Queensland, Australia, discusses whether cognitive and mindfulness-based approaches for pain engender benefits via theorized, therapy-specific mediators or via shared, nonspecific therapeutic factors.

Human Spinal Cord Neuroimaging of Chronic Pain and Opioid Use

Katherine Martucci, PhD, Duke University, US discusses recent and ongoing research on human spinal cord activity related to pain and sensory processing; changes in spinal cord activity in individuals with chronic pain; and the effect of opioid use on spinal cord activity in individuals with chronic pain.