PAIN: Clinical Updates

PAIN: Clinical Updates is a channel of PAIN Reports as well as a section of this open access journal. Each edition is published within the journal, providing timely and accurate information about pain management and therapy on topics of interest to practitioners in various specialties.

All editions appear on the PAIN Reports site. Back issues on a wide array of topics appear in the archives below.

Guidelines for authors are available here.

Current Issues

PAIN: Clinical Updates

Persistent postsurgical pain in children and young people: prediction, prevention, and management

September 2017, Vol. 25, No. 3

This edition of PAIN: Clinical Updates addresses the following key points:

  1. Persistent postsurgical pain (PPSP) is a recognized complication following surgery in children with an estimated median prevalence of 20% at 12 months after surgery.
  2. Presurgical factors predictive of PPSP include presurgical pain intensity, child anxiety, child pain coping efficacy, and parental pain catastrophizing.
  3. Treatment of PPSP involves the creation of an individualized management plan informed by the biopsychosocial formulation and using multidisciplinary interventions.

Featured Authors:

Glyn Williams MBBS FRCA MD FFPMRCA, Richard F Howard MBBS FRCA FFPMRCA, Christina Liossi

PAIN: Clinical Updates

Preventing and treating medication overuse headache

June 2017, Vol. 25, No. 2

This edition of PAIN: Clinical Updates addresses the following key points:

  1. According to the current concept, medication overuse headache (MOH) is a secondary headache—a worsening of a pre-existing headache (usually a primary headache) owing to overuse of one or more attack-aborting or painrelieving medications.
  2. Medication overuse headache has a prevalence of around 1% to 2% in the general population and should be suspected in anyone presenting with chronic headache (headache .14 days per month).
  3. Migraine is the underlying headache disorder in most of the cases.
  4. Existing criteria (International Classification of Headache Disorders–3 beta) often make straightforward diagnosis, but controversies around these criteria exist, and other chronic headache disorders may sometimes be difficult to rule out.
  5. Any immediate relief medication has the potential to cause MOH.
  6. Treatment guidelines for MOH are based on expert consensus and include withdrawal strategies, treatment of withdrawal headache, and eventually prophylactic medication for the underlying headache.

Featured Authors:

Karl B. Alstadhaug, MD, PhD, Hilde K. Ofte, MD, PhD, Espen S. Kristoffersen, MD, PhD

Editorial Board


Pain Medicine


Michael Bennett, MD, FRCP, FFPMRCA
Cancer Pain, Palliative Care

Daniel Ciampi de Andrade, PhD

Felicia Cox, FRCN
Pain Management, Nursing

Roy Freeman, MB, ChB

Maria Adele Giamberardino, MD
Internal Medicine, Physiology

Deb Gordon, RN, DNP, FAAN
Anesthesiology, Pain Medicine

Simon Haroutounian, PhD
Pain Medicine, Clinical Pharmacology

Andreas Kopf, MD

Michael Nicholas, PhD

M.R. Rajagopal, MD
Pain Medicine, Palliative Medicine

Hans-Georg Schaible, MD

Claudia Sommer, MD

Takahiro Ushida, MD, PhD
Orthopedics, Rehabilitation Pain Medicine

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