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Papers of the Week


2022 Jun 24


Ir J Med Sci

Assessment of the circulatory concentrations of cathepsin D, cathepsin K, and alpha-1 antitrypsin in patients with knee osteoarthritis.

Authors

Khoshdel A, Forootan M, Afsharinasab M, Rezaian M, Abbasifard M
Ir J Med Sci. 2022 Jun 24.
PMID: 35749030.

Abstract

Evidence has shown that cysteine protease enzymes, such as cathepsin D, cathepsin A, cathepsin K, and alpha-1 antitrypsin (AAT) are involved in the chronic degenerative joint process. This study aimed to determine the potential involvement of cathepsin K, cathepsin D, and AAT in patients with osteoarthritis (OA).