Astrocytic GPR37L1: A new guardian against the onset and chronicity of neuropathic pain.
Authors
Kohro Y, Tsuda M
Abstract
In this issue of Neuron, Xu et al. demonstrate that activating GPR37L1, a G-protein-coupled receptor that negatively regulates astrocytes, suppresses the onset and maintenance of neuropathic pain, an intractable chronic pain caused by nerve damage, thereby serving as a therapeutic target.
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