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Papers of the Week


Papers: 5 Oct 2024 - 11 Oct 2024


2024 Oct 04


Headache


39364583

Characterization of rimegepant drug-drug interactions using the cytochrome P450 probe drugs, itraconazole, rifampin, fluconazole, and midazolam.

Authors

Bhardwaj R, Morris B, Matschke KT, Bertz R, Croop R, Liu J

Abstract

Reported here are the results of four rimegepant phase I studies, in healthy participants, aimed at determining the in vivo potential of rimegepant (75 mg) for cytochrome P450 (CYP) 3A4-related drug-drug interactions (DDIs).