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Papers of the Week
Identification of biomarkers and potential drug targets in osteoarthritis based on bioinformatics analysis and mendelian randomization.
Authors
Cheng F, Li M, Hua H, Zhang R, Zhu Y, Zhu Y, Zhang Y, Tong PAbstract
Osteoarthritis (OA) can lead to chronic joint pain, and currently there are no methods available for complete cure. Utilizing the Gene Expression Omnibus (GEO) database for bioinformatics analysis combined with Mendelian randomization (MR) has been widely employed for drug repurposing and discovery of novel therapeutic targets. Therefore, our research focus is to identify new diagnostic markers and improved drug target sites.