Molecular determinants of neutrophil extracellular vesicles that drive cartilage regeneration in inflammatory arthritis.
Authors
Thomas BL, Montero-Melendez T, Oggero S, Kaneva MK, Chambers D, Pinto AL, Nerviani A, Lucchesi D, Austin-Williams S, Hussain MT, Pitzalis C, Allen B, Malcangio M, Dell'Accio F, Norling LV, Perretti M
Abstract
This study was undertaken to establish the potential therapeutic profile of neutrophil-derived extracellular vesicles (EVs) in experimental inflammatory arthritis and associate pharmacological activity with specific EV components, focussing on microRNAs.
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