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Papers of the Week
Development and validation of a mouse model to investigate post surgical pain after laparotomy.
Authors
Martinez J, Maisey T, Ingram N, Kapur N, Beales PA, Jayne DGAbstract
Postoperative pain following abdominal surgery is a significant obstacle to patient recovery, often necessitating high analgesic doses associated with adverse effects like cognitive impairment and cardiorespiratory depression. Reliable animal models are crucial for understanding the pathophysiology of post surgical pain and developing more effective pain-relieving strategies.